The autocratic challenge to democracies, a two-systems rivalry, large dominance of realpolitik and the emergence of big tech powerhouses as global players are the strategic matches of our times. To this adds the COVID-19 pandemic as a polycrisis, for some, the end of the Unit-ed Nations.How would a digitalised, environmentally sustainable and gender-sensitive world look like in 2050?In the manifesto Future Global Governance , co-authors revisit the changed context for mul-tilateralism and view new forms of anticipatory human-centred governance. The book re-examines universalism, strategic autonomy and resilience against today s power projections.Ursula Werther-Pietsch (ed.) is a profound connoisseur of multilateral system thinking. She published widely on human security, UN peace and security architecture and the Collective System of Security.